mako1 Syllabification: (ma·ko)Pronunciation: /ˈmākō, ˈmäkō/ (also mako shark)Definition of mako noun (plural makos) a large fast-moving oceanic shark with a deep blue back and white underparts. Genus Isurus, family Lamnidae: two species Origin: mid 19th century: from Maorimako in other Oxford dictionaries Definition of mako in the British & World English dictionary