lupine1 Syllabification: (lu·pine)Pronunciation: /ˈlo͞opin/Definition of lupine noun a plant of the pea family, with deeply divided leaves and tall, colorful, tapering spikes of flowers. Genus Lupinus, family Leguminosae: several species, in particular the popular cultivar Russell lupine Origin: late Middle English: from Latin lupinuslupine in other Oxford dictionaries Definition of lupine in the British & World English dictionary