lunate Syllabification: (lu·nate)Pronunciation: /ˈlo͞oˌnāt/Definition of lunate adjective crescent-shaped. noun (also lunate bone) Anatomy a crescent-shaped carpal bone situated in the center of the wrist and articulating with the radius. Origin: late 18th century: from Latin lunatus, from luna 'moon'lunate in other Oxford dictionaries Definition of lunate in the British & World English dictionary