lockup Syllabification: (lock·up)Pronunciation: /ˈläkˌəp/Definition of lockup noun 1a jail, especially a temporary one. 2the locking up of premises for the night. the time of doing this:hurrying back to their dorms before lockup 3the action of becoming fixed or immovable:anti-lock braking helps prevent wheel lockup 4an investment in assets that cannot readily be realized or sold in the short term. lockup in other Oxford dictionaries Definition of lockup in the British & World English dictionary