lipoprotein Syllabification: (lip·o·pro·tein)Pronunciation: /ˌlipəˈprōˌtēn, ˌlī-/Definition of lipoprotein noun Biochemistry any of a group of soluble proteins that combine with and transport fat or other lipids in the blood plasma. lipoprotein in other Oxford dictionaries Definition of lipoprotein in the British & World English dictionary