ketene Syllabification: (ke·tene)Pronunciation: /ˈkēˌtēn/Definition of ketene noun Chemistry a pungent colorless reactive gas, used as an intermediate in chemical synthesis. Chemical formula: C2H2O any substituted derivative of this. Origin: early 20th century: from ketone + -eneketene in other Oxford dictionaries Definition of ketene in the British & World English dictionary