keratin Syllabification: (ker·a·tin)Pronunciation: /ˈkerətin/Definition of keratin noun a fibrous protein forming the main structural constituent of hair, feathers, hoofs, claws, horns, etc.. Derivatives keratinousPronunciation: /kəˈratn-əs/ adjective Origin: mid 19th century: from Greek keras, kerat- 'horn' + -in1keratin in other Oxford dictionaries Definition of keratin in the British & World English dictionary