karyotype Syllabification: (kar·y·o·type)Pronunciation: /ˈkarēəˌtīp/Definition of karyotype noun Biology & Medicine the number and visual appearance of the chromosomes in the cell nuclei of an organism or species. Derivatives karyotypicPronunciation: /ˌkarēəˈtipik/ adjective karyotype in other Oxford dictionaries Definition of karyotype in the British & World English dictionary