isopycnic Syllabification: (i·so·pyc·nic)Pronunciation: /ˌīsəˈpiknik/Definition of isopycnic adjective Biochemistry of or denoting ultracentrifugal separation techniques making use of differences in density between the components of a mixture. Origin: late 19th century: from iso- 'equal' + Greek puknos 'dense' + -icisopycnic in other Oxford dictionaries Definition of isopycnic in the British & World English dictionary