immunocompromised Syllabification: (im·mu·no·com·pro·mised)Pronunciation: /ˌimyənōˈkämprəˌmīzd, iˌmyo͞o-/Definition of immunocompromised adjective Medicine having an impaired immune system. immunocompromised in other Oxford dictionaries Definition of immunocompromised in the British & World English dictionary