hypoxia Syllabification: (hy·pox·i·a)Pronunciation: /hīˈpäksēə/Definition of hypoxia noun Medicine deficiency in the amount of oxygen reaching the tissues. oxygen deficiency in a biotic environment:aquatic hypoxiaDerivatives hypoxicPronunciation: /-sik/ adjective Origin: 1940s: from hypo- (denoting an element in a low valency) + oxygen + -ia1hypoxia in other Oxford dictionaries Definition of hypoxia in the British & World English dictionary