hyperimmune Syllabification: (hy·per·im·mune)Pronunciation: /ˌhīpəriˈmyo͞on/Definition of hyperimmune adjective Medicine having a high concentration of antibodies produced in reaction to repeated injections of an antigen. Derivatives hyperimmunizedPronunciation: /-ˈimyəˌnīzd/ adjective hyperimmune in other Oxford dictionaries Definition of hyperimmune in the British & World English dictionary