hydroxyapatite Syllabification: (hy·drox·y·a·pa·tite)Pronunciation: /hīˌdräksēˈapəˌtīt/Definition of hydroxyapatite noun a mineral of the apatite group that is the main inorganic constituent of tooth enamel and bone, although it is rare in rocks. hydroxyapatite in other Oxford dictionaries Definition of hydroxyapatite in the British & World English dictionary