gynecomastia Syllabification: (gyn·e·co·mas·ti·a)Pronunciation: /ˌgīnəkōˈmastēə/ (British gynaecomastia)Definition of gynecomastia noun Medicine enlargement of a man’s breasts, usually due to hormone imbalance or hormone therapy. gynecomastia in other Oxford dictionaries Definition of gynecomastia in the British & World English dictionary