gesso Syllabification: (ges·so)Pronunciation: /ˈjesō/Definition of gesso noun (plural gessoes) a hard compound of plaster of Paris or whiting in glue, used in sculpture or as a base for gilding or painting on wood. Derivatives gessoed adjective Origin: late 16th century: Italian, from Latin gypsum (see gypsum)gesso in other Oxford dictionaries Definition of gesso in the British & World English dictionary