fluvoxamine Syllabification: (flu·vox·a·mine)Pronunciation: /flo͞oˈväksəˌmēn, -min/Definition of fluvoxamine noun Medicine a synthetic antidepressant drug that acts by prolonging the effect of the neurotransmitter serotonin on the brain. fluvoxamine in other Oxford dictionaries Definition of fluvoxamine in the British & World English dictionary