exospore Syllabification: (ex·o·spore)Pronunciation: /ˈeksōˌspôr/Definition of exospore noun 1the outer layer of the membrane in some spores. 2a spore formed by separation and release from a sporophore, the spore-bearing structure of a fungus. Derivatives exosporalPronunciation: /ˌeksəˈspôrəl/ adjective