dysplasia Syllabification: (dys·pla·sia)Pronunciation: /disˈplāZHə/Definition of dysplasia noun Medicine the enlargement of an organ or tissue by the proliferation of cells of an abnormal type, as a developmental disorder or an early stage in the development of cancer. Origin: 1930s: from dys- 'bad' + Greek plasis 'formation'dysplasia in other Oxford dictionaries Definition of dysplasia in the British & World English dictionary