duotone Syllabification: (du·o·tone)Pronunciation: /ˈd(y)o͞oəˌtōn/Definition of duotone noun a halftone illustration made from a single original with two different colors at different screen angles. the technique or process of making duotone illustrations:the best images that duotone can produceduotone in other Oxford dictionaries Definition of duotone in the British & World English dictionary