detune Syllabification: (de·tune)Pronunciation: /dēˈt(y)o͞on/Definition of detune verb [with object] 1cause (a musical instrument) to become out of tune. 2 (usually as adjective detuned) reduce the performance or efficiency of (a motor vehicle or engine) by adjustment. 3change the frequency of (an oscillatory system such as a laser) away from a state of resonance. detune in other Oxford dictionaries Definition of detune in the British & World English dictionary