desex Syllabification: (de·sex)Pronunciation: /dēˈseks/Definition of desex verb [with object] (usually as adjective desexed) 1deprive (someone) of sexual qualities or attraction:Lawrence portrays feminists as shrill, humorless, and desexed 2castrate or spay (an animal). desex in other Oxford dictionaries Definition of desex in the British & World English dictionary