dermis Syllabification: (der·mis)Pronunciation: /ˈdərmis/Definition of dermis noun technical the skin. Anatomy the thick layer of living tissue below the epidermis that forms the true skin, containing blood capillaries, nerve endings, sweat glands, hair follicles, and other structures. Derivatives dermalPronunciation: /-məl/ adjective dermicPronunciation: /-mik/ adjective ( rare)Origin: mid 19th century: modern Latin, suggested by epidermisdermis in other Oxford dictionaries Definition of dermis in the British & World English dictionary