cytosol Syllabification: (cy·to·sol)Pronunciation: /ˈsītəˌsäl, -ˌsôl/Definition of cytosol noun Biology the aqueous component of the cytoplasm of a cell, within which various organelles and particles are suspended. Derivatives cytosolicPronunciation: /ˌsītəˈsälik, -ˈsôlik/ adjective cytosol in other Oxford dictionaries Definition of cytosol in the British & World English dictionary