crossbreed Syllabification: (cross·breed)Pronunciation: /ˈkrôsˌbrēd/Translate crossbreed | into Italian | into Spanish Definition of crossbreed noun an animal or plant produced by mating or hybridizing two different species, breeds, or varieties: [as modifier]:a crossbreed Labrador verb [with object] produce (an animal or plant) by crossbreeding: (as adjective crossbred)a crossbred puppy hybridize (a breed, species, or variety) with another. [no object] (of an animal or plant) breed with a different breed, species, or variety. crossbreed in other Oxford dictionaries Definition of crossbreed in the British & World English dictionary