coagulase Syllabification: (co·ag·u·lase)Pronunciation: /kōˈagyəˌlās, -ˌlāz/Definition of coagulase noun Biochemistry a bacterial enzyme that brings about the coagulation of blood or plasma and is produced by disease-causing forms of staphylococcus. coagulase in other Oxford dictionaries Definition of coagulase in the British & World English dictionary