cleome Syllabification: (cle·o·me)Pronunciation: /klēˈōmē/Definition of cleome noun a plant of a chiefly tropical genus that includes the spider flower. Cleomes are noted for their long stamens. Genus Cleome, family Capparidaceae Origin:modern Latin, from Greek, denoting a different plantcleome in other Oxford dictionaries Definition of cleome in the British & World English dictionary