asparagine Syllabification: (as·par·a·gine)Pronunciation: /əˈsparəˌjēn, -jin/Definition of asparagine noun Biochemistry a hydrophilic amino acid that is a constituent of most proteins. An amide of aspartic acid; chemical formula: CONH2CH2CH(NH2)COOH Origin: early 19th century: from asparagus (which contains it) + -ine4asparagine in other Oxford dictionaries Definition of asparagine in the British & World English dictionary