adenosine Syllabification: (a·den·o·sine)Pronunciation: /əˈdenəˌsēn, -sin/Definition of adenosine noun Biochemistry a compound consisting of adenine combined with ribose, one of four nucleoside units in RNA. Origin: early 20th century: blend of adenine and riboseadenosine in other Oxford dictionaries Definition of adenosine in the British & World English dictionary