acalculia Syllabification: (a·cal·cu·li·a)Pronunciation: /ˌākalˈkyo͞olēə/Definition of acalculia noun Medicine loss of the ability to perform simple arithmetic calculations, typically resulting from disease or injury of the parietal lobe of the brain. Origin: early 20th century: from a-1 'not' + Latin calculare 'calculate' + -ia1acalculia in other Oxford dictionaries Definition of acalculia in the British & World English dictionary