Tenochtitlán Syllabification: (Te·noch·ti·tlán)Pronunciation: /təˌnôCHtētˈlän/Definition of Tenochtitlán the ancient capital of the Aztec empire, founded circa 1320. In 1521, the Spanish conquistador Cortés destroyed it and established Mexico City on its site. Tenochtitlán in other Oxford dictionaries Definition of Tenochtitlán in the British & World English dictionary