Sacajawea Syllabification: (Sac·a·ja·we·a)Pronunciation: /ˌsakəjəˈwēə, -ˈwāə/Definition of Sacajawea (c.1786–1812), Shoshone Indian guide and interpreter; also Sacagawea. She joined the Lewis and Clark expedition in what is now North Dakota and guided their travels through the wilderness and across the Rockies 1804–06. Origin:from Hidatsa tsakaka-wia, literally 'bird-woman'