Panthalassa Syllabification: (Pan·thal·as·sa)Pronunciation: /ˌpanTHəˈlasə/Definition of Panthalassa a universal sea or single ocean, such as would have surrounded Pangaea. Origin: late 19th century: from pan- 'all' + Greek thalassa 'sea'Panthalassa in other Oxford dictionaries Definition of Panthalassa in the British & World English dictionary