Milesian Syllabification: (Mi·le·sian)Pronunciation: /məˈlēZHən, mī-/Definition of Milesian noun a native or inhabitant of ancient Miletus. adjective of or relating to Miletus or its inhabitants. Origin: mid 16th century: via Latin from Greek Milēsios + -anMilesian in other Oxford dictionaries Definition of Milesian in the British & World English dictionary