Manhattanite Syllabification: (Man·hat·tan·ite)Pronunciation: /ˌmanˈhatəˌnīt/Definition of Manhattanite noun a native or inhabitant of the borough of Manhattan, in New York City: Manhattanites don’t want their neighborhood uprooted by expresswaysManhattanite in other Oxford dictionaries Definition of Manhattanite in the British & World English dictionary