Lydia Syllabification: (Lyd·i·a)Pronunciation: /ˈlidēə/Definition of Lydia an ancient region of western Asia Minor, south of Mysia and north of Caria. It became a powerful kingdom in the 7th century bc but in 546 Croesus, its last king, was defeated by Cyrus and it was absorbed into the Persian empire. Lydia in other Oxford dictionaries Definition of Lydia in the British & World English dictionary