Chickasaw Syllabification: (Chick·a·saw)Pronunciation: /ˈCHikəˌsô/Definition of Chickasaw noun (plural same or Chickasaws) 1a member of an American Indian people formerly resident in Mississippi and Alabama, and now in Oklahoma. 2the Muskogean language of the Chickasaw. adjective relating to the Chickasaw or their language. Origin:the name in ChickasawChickasaw in other Oxford dictionaries Definition of Chickasaw in the British & World English dictionary