Chesapeake Bay Syllabification: (Ches·a·peake Bay)Pronunciation: /ˈCHesəˌpēk/Definition of Chesapeake Bay a large inlet of the North Atlantic Ocean on the US coast that extends north for 200 miles (320 km) through the states of Virginia and Maryland. Chesapeake Bay in other Oxford dictionaries Definition of Chesapeake Bay in the British & World English dictionary