Alsace Syllabification: (Al·sace)Pronunciation: /alˈsas, -ˈsās/Translate Alsace | into Italian Definition of Alsace a region of northeastern France, on the borders with Germany and Switzerland. It was annexed by Prussia, along with part of Lorraine, to form Alsace-Lorraine after the Franco-Prussian War of 1870–71. It was restored to France after World War I. Alsace in other Oxford dictionaries Definition of Alsace in the British & World English dictionary